Definition Of Visceral Metastases

With a multitude of new and emerging treatments a special effort to design clinical trials for those with visceral disease should be undertaken.

Definition of visceral metastases. The proportion of men with metastatic prostate cancer who develop visceral metastases rose from 26 in 2009 to 40 in 2016 a study found. What are visceral metastases exactly. In the tax 327 phase iii trial men receiving docetaxel or mitoxantrone every 3 weeks. Extensive liver metastases can lead to jaundice and biochemical evidence of liver failure.

Visceral metastases often present with organ dysfunction. This is clearly a poor prognosis group and appears to be underrepresented in clinical trials. Although less common than bone metastases in prostate cancer the presence of visceral soft tissue metastases is adversely prognostic in men with metastatic castration resistant prostate cancer mcrpc. Devon webster answered 21 years experience medical oncology cancer in organs.

Metastases to bone are not visceral metastases. Visceral lesions derived from liver and lymph nodes were found to express an angiogenic profile different from that of liver metastases alone with significant relative overexpression of the proangiogenic factor angiopoietin 2. In the case of liver metastases the first symptom may be liver function abnormalities or pain due to stretching of the hepatic capsule. The prognostic outlook regarding the specific location of the visceral metastasis is unclear.

Metastases or areas of cancer spread to the liver lungs or other organs in the body. Nci s dictionary of cancer terms provides easy to understand definitions for words and phrases related to cancer and medicine.