Definition Of Vaccinia Virus

Vaccination with vaccinia virus has been directly responsible for the successful eradication of smallpox variola.

Definition of vaccinia virus. Look it up now. Virus vi rus any member of a unique class of infectious agents which were originally distinguished by their smallness hence they were described as filtrable because of their ability to pass through fine ceramic filters that blocked all cells including bacteria and their inability to replicate outside of and without assistance of a living. The tk and vaccinia growth factor gene deletions in intratumorally administered vaccinia virus vvdd cdsr help to. Vaccinia definition is a poxvirus species vaccinia virus of the genus orthopoxvirus that differs from but is closely related to the viruses causing smallpox and cowpox and that includes a strain used in making vaccines against smallpox.

The cowpox virus which is used to vaccinate against smallpox. Vaccinia gangreno sa generalized vaccinia with failure to develop antibodies against the virus due to agammaglobulinemia with spreading necrosis at the site and metastasis of lesions throughout the body. A cutaneous or systemic reaction to vaccination with the smallpox vaccine as for example in congenital vaccinia and progressive vaccinia. The usually mild cutaneous and sometimes systemic reaction in individuals who have been inoculated with smallpox vaccine.

Vaccinia definition a variant of the cowpox virus that became established in vaccines derived from cowpox inoculated humans. Although the exact origins of vaccinia virus are uncertain vaccinia may represent a hybrid of the variola and cowpox viruses. A highly tumor selective vaccinia virus vv with an engineered double deletion dd of the thymidine kinase tk and vaccinia growth factor genes and additions of both a cytosine deaminase cd gene and a somatostatin receptor sr gene with potential oncolytic viral activity. Vaccinia virus synonyms vaccinia virus pronunciation vaccinia virus translation english dictionary definition of vaccinia virus.

It has a linear double stranded dna genome approximately 190 kbp in length which encodes approximately 250 genes the dimensions of the virion are roughly 360 270 250 nm with a mass of approximately 5 10 fg.